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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANLN All Species: 13.64
Human Site: S99 Identified Species: 27.27
UniProt: Q9NQW6 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQW6 NP_061155.2 1124 124199 S99 S A K S C S P S P V S P Q V Q
Chimpanzee Pan troglodytes XP_001169875 1125 124324 S99 S A K S C S P S P V S P Q V Q
Rhesus Macaque Macaca mulatta XP_001103129 1127 124400 S99 S A K S C S P S P V S P Q V Q
Dog Lupus familis XP_539518 1121 123493 S99 S A K P C P P S P A P P Q A Q
Cat Felis silvestris
Mouse Mus musculus Q8K298 1121 122775 M98 V A K P C S P M P A P R Q A K
Rat Rattus norvegicus XP_225479 975 107264 S10 K L R R H W D S E I T D D V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418836 1121 123757 V98 S P S H R S P V M N S E L H G
Frog Xenopus laevis Q801E2 1116 122812 A99 L P K T E L S A V A S H Q Q L
Zebra Danio Brachydanio rerio NP_001096146 1153 127336 P99 D P M T D Q K P P L A P T T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V4P1 1239 136015 G131 D E E Q A E G G A L N P L L E
Honey Bee Apis mellifera XP_624050 1031 115155 K66 S S I K S P R K S T S K C S T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795668 1146 126808 V112 D F E E E E G V P A A P A V K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.9 87.8 N.A. 80.3 70.3 N.A. N.A. 63.6 56.4 49 N.A. 23.3 25 N.A. 24.7
Protein Similarity: 100 99.6 98.1 92.1 N.A. 87.1 77.1 N.A. N.A. 77.3 71.7 66.3 N.A. 42.7 44.4 N.A. 43.2
P-Site Identity: 100 100 100 66.6 N.A. 46.6 13.3 N.A. N.A. 26.6 20 13.3 N.A. 6.6 13.3 N.A. 20
P-Site Similarity: 100 100 100 66.6 N.A. 53.3 33.3 N.A. N.A. 26.6 33.3 33.3 N.A. 40 20 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 42 0 0 9 0 0 9 9 34 17 0 9 17 0 % A
% Cys: 0 0 0 0 42 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 25 0 0 0 9 0 9 0 0 0 0 9 9 0 0 % D
% Glu: 0 9 17 9 17 17 0 0 9 0 0 9 0 0 9 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 17 9 0 0 0 0 0 0 9 % G
% His: 0 0 0 9 9 0 0 0 0 0 0 9 0 9 0 % H
% Ile: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % I
% Lys: 9 0 50 9 0 0 9 9 0 0 0 9 0 0 17 % K
% Leu: 9 9 0 0 0 9 0 0 0 17 0 0 17 9 9 % L
% Met: 0 0 9 0 0 0 0 9 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 9 9 0 0 0 0 % N
% Pro: 0 25 0 17 0 17 50 9 59 0 17 59 0 0 0 % P
% Gln: 0 0 0 9 0 9 0 0 0 0 0 0 50 9 34 % Q
% Arg: 0 0 9 9 9 0 9 0 0 0 0 9 0 0 0 % R
% Ser: 50 9 9 25 9 42 9 42 9 0 50 0 0 9 9 % S
% Thr: 0 0 0 17 0 0 0 0 0 9 9 0 9 9 9 % T
% Val: 9 0 0 0 0 0 0 17 9 25 0 0 0 42 9 % V
% Trp: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _